Home-BRAC

  • Research type

    Research Study

  • Full title

    EVALUATION OF THE IMPACT OF THE SIMEOX AIRWAY CLEARANCE MEDICAL DEVICE AT HOME, COMBINED WITH REMOTE PHYSIOTHERAPY, ON THE QUALITY OF LIFE AND PULMONARY EXACERBATIONS IN PATIENTS WITH NON-CYSTIC FIBROSIS BRONCHIECTASIS, COMPARED WITH ENHANCED STANDARD OF CARE

  • IRAS ID

    351359

  • Contact name

    Laurent MORIN

  • Contact email

    laurent.morin@inogen.net

  • Sponsor organisation

    Physio-Assist – INOGEN Group

  • Duration of Study in the UK

    3 years, 2 months, 1 days

  • Research summary

    HOME-BRAC study aims at evaluating the impact of the SIMEOX airway clearance medical device, combined with remote physiotherapy at home, on the quality of life and the pulmonary exacerbations of patients with non-cystic fibrosis bronchiectasis, compared with enhanced standard of care. The SIMEOX device (Physio-Assist, INOGEN group) is an innovative medical device for draining the bronchial tree. This device allows for mobilizing bronchial secretions. Thanks to a series of vibrations, it allows for reducing mucus viscosity and thus facilitates expectoration. An initial short-term pilot study, conducted over 3 months, demonstrated in particular a high level of satisfaction in the patients that benefitted from the SIMEOX in conjunction with the remote therapy, giving an average score of 9/10 for this treatment method. In this study, its impact over a longer term will be determined.

  • REC name

    East of England - Cambridge Central Research Ethics Committee

  • REC reference

    25/EE/0076

  • Date of REC Opinion

    17 Jul 2025

  • REC opinion

    Further Information Favourable Opinion