Home-based exercise in Renal Transplant patients: The ECSERT Study
Research type
Research Study
Full title
A Pilot randomised controlled trial of the effects of a structured, home-based exercise program on Cardiovascular StructurE and function in Renal Transplant recipients. The ECSERT study
IRAS ID
263656
Contact name
Matthew PM Graham-Brown
Contact email
Sponsor organisation
TBC
Duration of Study in the UK
2 years, 11 months, 30 days
Research summary
Although patients who have received a kidney transplant have better health than patients on dialysis, heart problems are still the commonest cause of death for kidney transplant recipients. This is because diseases like high blood pressure and diabetes are more common in patients with kidney transplants as well as factors related to having kidney disease itself and the medications transplant recipients have to take to stop them rejecting their transplanted kidney. Exercise is known to help with heart disease in lots of conditions and improves many of the risk factors known to cause heart disease in kidney transplant recipients. This study will investigate whether an individualised, home-based, exercise program improves heart disease in kidney transplant recipients. The study is a randomised controlled trial, with half the patients completing the 12 week exercise programme and the other half continuing with their normal care. We will use detailed MRI scans to assess patient’s hearts and blood vessels at the start and end of the study. We also assess changes in physical function, exercise capacity, blood markers of heart disease, changes in body type and quality of life measures assessed with questionnaires.
REC name
East Midlands - Nottingham 2 Research Ethics Committee
REC reference
19/EM/0290
Date of REC Opinion
14 Oct 2019
REC opinion
Further Information Favourable Opinion