Hip Injection Trial (HIT)
Research type
Research Study
Full title
Improving outcomes for patients with hip osteoarthritis: a randomised controlled trial
IRAS ID
163306
Contact name
Jacqueline Gray
Contact email
Sponsor organisation
Keele University
Eudract number
2014-003412-37
ISRCTN Number
ISRCTN50550256
Duration of Study in the UK
2 years, 1 months, 31 days
Research summary
Hip osteoarthritis (OA) is a very common condition that causes pain and can affect ability to do day to day activities.
There have been several studies about treatments for OA including joint injections. However, little is known about the best treatments for patients with moderate to severe hip OA.
This trial aims to find out whether best current treatment in addition to a single steroid and local anaesthetic injection is effective at reducing pain in patients with hip OA when compared to best current treatment and a single local anasthetic injection, or best current treatment alone. We will study the effects of these 3 treatments over 6 months.
Participants will be recruited from primary care referrals to orthopaedics, rheumatology and two musculoskeletal services in Staffordshire. Patients aged 40 years and over and who have experienced pain from hip OA for at least 6 weeks will be eligible for inclusion.
The steroid is a drug called "Triamcinolone Acetonide". This drug is widely used to treat joint pain and arthritis. In this trial, one injection will be given at one time point. Each participant will receive either best current treatment and a single steroid and local anaesthetic injection, best current treatment and a local anaesthetic injection, or best current treatment alone. Participants will be asked to complete up to 5 questionnaires over 6 months.
REC name
North West - Greater Manchester South Research Ethics Committee
REC reference
15/NW/0546
Date of REC Opinion
27 Jul 2015
REC opinion
Further Information Favourable Opinion