HIP-ATTACK-2 Trial
Research type
Research Study
Full title
HIP fracture Accelerated surgical TreaTment And Care tracK 2 (HIP-ATTACK-2) Trial
IRAS ID
321727
Contact name
Marcela Paola Vizcaychipi
Contact email
Sponsor organisation
Population Health Research institute
Clinicaltrials.gov Identifier
Clinicaltrials.gov Identifier
C&W22/044, C&W22/044
Duration of Study in the UK
2 years, 0 months, 6 days
Research summary
A hip fracture is a common injury in the elderly with approximately 3 million occurring annually around the world (76,000 in the UK). The incidence is increasing as the population ages. 30 day mortality from this condition is about 6-10%.
A previous study, HIP-ATTACK-1, was carried out to determine if accelerated surgery compared to standard of care improves clinical outcomes in patients with a hip fracture. HIP ATTACK-1 demonstrated that accelerated surgery was feasible and safe, even in patients with acute medical conditions. Its results further suggested that an increased troponin level identifies patients who are not tolerating the hip fracture stress,and could benefit from expedited care.
We will conduct a large international randomized controlled trial (RCT), HIP-ATTACK-2, to assess the impact of accelerated medical clearance and surgery versus standard care in hip fracture patients who also have an acute myocardial injury when they present to the hospital.
REC name
East of England - Cambridge Central Research Ethics Committee
REC reference
25/EE/0190
Date of REC Opinion
17 Dec 2025
REC opinion
Further Information Favourable Opinion