HICAM Version 1.0
Research type
Research Study
Full title
First use of a hybrid gamma camera for sentinel lymph node localisation in patients undergoing surgery for primary breast cancer
IRAS ID
187800
Contact name
Kwok Leung Cheung
Contact email
Sponsor organisation
University of Nottingham
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 12 months, 0 days
Research summary
Standard gamma cameras are very big machines that cannot be moved. This restricts the type of patients who can benefit from this technology, as only patients who can attend the clinic have access to diagnostic tests the device offers. The Universities of Nottingham and Leicester have developed a novel hand held hybrid compact gamma camera (hybrid camera). This hybrid camera can take both a photograph and a gamma image of sites in the body at the patient bedside/operating theatre. This study aims to evaluate the imaging capabilities of the hybrid camera in sentinel lymph node biopsy procedure during breast cancer surgery. It is anticipated that this new hybrid camera could improve the accuracy and simplify sentinel lymph node detection by providing combined optical and gamma imaging. This is a single centre prospective, non-randomised and non-blinded interventional research study using the hybrid camera in addition to the standard sentinel lymph node biopsy procedures provided by NHS treatment. The hybrid camera will be used to take several images during the surgery. The detection rates of sentinel lymph node with the standard method and the hybrid camera will be compared. The duration of the study is one year. We will invite females in Royal Derby Hospital with breast cancer aged greater than 18 years who will undergo the sentinel lymph node biopsy procedure to take part in this study. The study is funded by a Biocatalyst Award from the Technology Strategy Board (Innovate UK).
REC name
Yorkshire & The Humber - Sheffield Research Ethics Committee
REC reference
16/YH/0008
Date of REC Opinion
17 Mar 2016
REC opinion
Further Information Favourable Opinion