HI-CARE
Research type
Research Study
Full title
Hair Isotope Analysis for Early Cancer Detection
IRAS ID
355019
Contact name
Gunter G Kuhnle
Contact email
Sponsor organisation
University of Reading
Duration of Study in the UK
4 years, 11 months, 31 days
Research summary
Cancer is a major health challenge, and early detection is crucial for improving patient outcomes. Research has shown that cancer can alter the way the body processes nutrients. This study aims to explore whether these metabolic changes can be detected through a simple, non-invasive method: analysing hair. Hair grows slowly over time, potentially capturing subtle metabolic changes that occur during cancer development. By studying the nitrogen stable isotope composition in hair samples donated by individuals diagnosed with cancer, we aim to identify potential early markers of the disease. Participants will be asked to donate a small strand of hair, which will be analysed using a laboratory technique called Isotope Ratio Mass Spectrometry (IRMS). The findings from this study could contribute to new, non-invasive screening tools for early cancer detection.
REC name
London - Dulwich Research Ethics Committee
REC reference
25/LO/0455
Date of REC Opinion
9 Sep 2025
REC opinion
Further Information Favourable Opinion