HFpEF Evaluation and Recognition by CMR
Research type
Research Study
Full title
PReserved Ejection Fraction Evaluation and Recognition by Cardiac Magnetic Resonance: the PREFER-CMR Programme
IRAS ID
301141
Contact name
Pankaj Garg
Contact email
Duration of Study in the UK
10 years, 0 months, 0 days
Research summary
Heart failure with preserved ejection fraction (HFpEF) is common and becoming one of the leading causes of death in patients with heart disease. Current non-invasive tests are not accurate enough to detect or diagnose HFpEF. This results in delayed diagnosis and early death for thousands of patients. Recent development in cutting-edge, fast four-dimensional flow (4D flow) magnetic resonance imaging (MRI) techniques which can reliably assess three-dimensional blood-flow inside the heart over-time (the fourth dimension). Our team has invented 4D flow MRI methods that can better detect raised pressures inside the heart associated with HFpEF. It requires no additional equipment, risk or expense, and enables accurate diagnosis of HFpEF. Working with world-leading cardiologists, engineers, scientists and companies, our ambition for the Fellowship is to further develop 4D flow MRI methods that will help doctors better detect and diagnosis and provide early treatment to patients with HFpEFand hence save thousands of lives.
REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
21/NE/0149
Date of REC Opinion
21 Sep 2021
REC opinion
Further Information Favourable Opinion