HeartGuide BP LVMI study
Research type
Research Study
Full title
Relationship between blood pressure profiles measured by a wrist-type blood pressure monitor (HeartGuide) and left ventricular mass index
IRAS ID
280191
Contact name
Bryan Williams
Contact email
ISRCTN Number
ISRCTN69980195
Clinicaltrials.gov Identifier
Funder Contract ID , 5196073; Worktribe Project ID, 4206384; Data Protection Registration Number, Z6364106/2020/10/76
Duration of Study in the UK
1 years, 6 months, 0 days
Research summary
Accurate measurement of blood pressure (BP) is important in managing risk for cardiovascular disease such as heart attack and stroke. BP has been routinely measured at a Doctor's surgery for many years, but increasingly patients are measuring their own BP at home or at work. There is evidence that this may provide a better measurement of the patient’s true BP. In this study we plan to evaluate a wrist watch-like BP monitor to see whether it is a convenient way for patients to measure their own BP and whether it provides reliable information about the effects of BP on the structure of their heart.
The structure of the heart is affected by high BP. Specifically, there is a thickening of the muscular wall of the heart because it has to pump against a high pressure. This thickening of the heart muscle is a good predictor of the BP load on the heart and a good predictor of future risk of heart disease and stroke. We will measure the structure of the heart muscle using cardiac MRI (cMRI), which is the most accurate way of quantifying the thickness of the heart muscle. We will relate the BP measurements using the wrist-type monitor to the thickness of heart muscle in different patients with high BP to define whether this wrist-type BP monitor is a good predictor of the effects of BP on the heart. We will also see whether it is a better predictor than the usual ways we measure BP in routine clinical practice. The results of this study will tell us whether this new wrist-type BP monitor might provide a more convenient way for patients to monitor their BP.
REC name
London - Fulham Research Ethics Committee
REC reference
20/PR/0953
Date of REC Opinion
25 Jan 2021
REC opinion
Favourable Opinion