Healthcare decision making in ALS patients

  • Research type

    Research Study

  • Full title

    The effects of ALS-associated communication changes on decision-making and interaction with health care professionals (HCPs)

  • IRAS ID

    302489

  • Contact name

    Ammar Al-Chalabi

  • Contact email

    ammar.al-chalabi@kcl.ac.uk

  • Sponsor organisation

    Kings College London

  • Duration of Study in the UK

    3 years, 0 months, 31 days

  • Research summary

    The study is asking how the decision-making process occurs during interactions between the patients with amyotrophic lateral sclerosis (ALS) and the health care professionals (HCPs). The overall aim is to produce an analysis of conversations between patients with ALS and HCPs and to identify the decision-making process through these interactions.

    The hypothesis is that the speech and cognitive changes of ALS severely impact the ability to make decisions and communicate with key people. The aim is to determine the main strategies used by the patients to communicate (both verbally and non-verbally) and the major purpose of communication. Additionally, the goal is to determine the major communication goals, changes and problems that are faced by the ALS patients, their partners and healthcare workers.

    Video recordings will be made of the patients interacting with their partners and health care professionals (HCPs). A qualitative descriptive ethnographic design utilising the methods of Conversation Analysis will be used. The Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) will be used to assess functional ability.The Edinburgh Cognitive and Behavioural ALS Screen (ECAS) will be used to assess cognitive and behavioural changes in ALS patients.
    The Hospital Anxiety and Depression Scale (HADS) will be used to measure the patients’ symptoms of anxiety and depression.
    The study will be conducted at King's College Hospital within a period of 12 months.

  • REC name

    Yorkshire & The Humber - Bradford Leeds Research Ethics Committee

  • REC reference

    22/YH/0154

  • Date of REC Opinion

    23 Aug 2022

  • REC opinion

    Further Information Favourable Opinion