HBM4EU Occupational Biomonitoring Study on Diisocyanates v2
Research type
Research Study
Full title
HBM4EU Occupational Biomonitoring Study on Diisocyanate Exposure
IRAS ID
285471
Contact name
Kate Jones
Contact email
Sponsor organisation
HSE
Duration of Study in the UK
2 years, 3 months, 31 days
Research summary
The proposal presented here and within the supporting documentation describes a study, which forms part of a pan-European project called HBM4EU (Human Biomonitoring for Europe). One work strand within this study is investigating workers’ exposure to hazardous chemicals in the workplace.
The main aims of the current proposal are to provide new data on exposures to diisocyanates in specific sectors based on harmonized sampling protocols, to investigate the usability of different biomarkers in the assessment of exposure to diisocyanates, and finally to provide background data for the setting of EU wide limit values for diisocyanates and for the follow-up of the effectiveness of diisocyanate REACH restriction in different countries.
The study will be conducted in five countries; UK, Finland, Belgium, France and the Netherlands during 2020-2022. Please find the study work plan attached with this ethics application (Appendix 1). It outlines the study protocol for HBM4EU. Please note however, that the protocol is for the entire HBM4EU occupational work strand spanning all countries and experts involved and some aspects of the protocol are not relevant to the UK's involvement in this study. In particular, we will not be undertaking any blood sampling and/or analysis and exhaled nitric oxide (FeNO) will be the only effect marker measured
However, the consent forms, information sheets and questionnaires that are presented as separate appendices within this ethics application have been adapted to be specific to the UK study.REC name
East Midlands - Derby Research Ethics Committee
REC reference
20/EM/0188
Date of REC Opinion
8 Sep 2020
REC opinion
Further Information Favourable Opinion