Handgrip strength and exercise capacity in heart failure
Research type
Research Study
Full title
Does handgrip strength relate to exercise capacity and other clinical variables in patients with and without heart failure?
IRAS ID
192807
Contact name
Klaus Witte
Contact email
Sponsor organisation
University of Leeds
Duration of Study in the UK
0 years, 6 months, 1 days
Research summary
We want to determine whether handgrip strength and endurance relates to exercise capacity measured formally using cardiopulmonary exercise testing in patients with and without heart failure.
To do this we will invite consecutive patients attending the CPX laboratory at LGI to perform two handgrip strength assessments one to establish maximum grip power and a second of repeated submaximal grips to establish endurance. These data will then be linked to the patients' clinical data to see if they correlate with other markers of severity. We aim to establish that skeletal muscle strength is impaired even in muscles that do not traditionally detrain in patients with cardiovascular disease.
We will also approach patients without heart failure booked for a CPX test. This will be done by a review of the referral card and a check on the electronic patient record to determine eligibility by Joshua Woodcock-Shaw. Patients without heart failure will be asked to do the test only once.REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
15/NE/0371
Date of REC Opinion
29 Oct 2015
REC opinion
Favourable Opinion