HAEFiT v1.0 - Hereditary Angioedema and Fitness Tracking

  • Research type

    Research Study

  • Full title

    A prospective cohort study of adults with hereditary angioedema to assess the feasibility of using a wearable fitness tracking device to investigate relationships between attack frequency and physical activity.

  • IRAS ID

    251660

  • Contact name

    Emily Carne

  • Contact email

    emily.carne@wales.nhs.uk

  • Sponsor organisation

    Cardiff and Vale University Local Health Board

  • Duration of Study in the UK

    2 years, 11 months, 31 days

  • Research summary

    HAEFiT aims to explore the feasibility of using fitness tracking devices to assess the relationship between angioedema attack frequency and measurements made by a fitness tracking device of steps taken per day and exercise intensity. We hypothesise that physical activity may act as a trigger for angioedema attacks, but also may improve disease control . We also hypothesise that there is a relationship between sleep quality and angioedema attack frequency , in that poor sleep quality may be associated with increased frequency due to resulting fatigue or underlying stress . Objective measurement of these effects may be a more reliable and accurate way to assess symptoms and disease impact than conventional patient-reported measures.

  • REC name

    Wales REC 5

  • REC reference

    20/WA/0215

  • Date of REC Opinion

    25 Aug 2020

  • REC opinion

    Favourable Opinion