GSK PATCH questionnaire
Research type
Research Study
Full title
Real-world evaluation of treatments received prior to enrolment in the CALM-1 and CALM-2 clinical trials using the Patients after Therapies for Cough (PATCH) questionnaire
IRAS ID
373703
Contact name
Alyn Hugh Morice
Contact email
Sponsor organisation
GSK
Duration of Study in the UK
0 years, 4 months, 29 days
Research summary
Chronic cough is a long-lasting condition (lasting more than 8 weeks) that can significantly affect daily life, including sleep, communication, and overall wellbeing. For some people, the cough continues despite treatment (referred to as refractory chronic cough) or has no clear cause. Treatment options are currently limited, and patients often try multiple therapies without full relief.
This study aims to better understand what treatments patients have received for chronic cough before taking part in two existing clinical trials (CALM-1 and CALM-2). These trials are investigating a potential new treatment called camlipixant. However, they only collected information on treatments used in the short period before patients joined the trials, meaning the full treatment history is not well understood.
To address this, researchers will contact adults who previously participated in the CALM trials and invite them to take part in this study. Participants who agree will complete a questionnaire (called PATCH) during a short telephone interview or based on their medical records. They will be asked about the types of treatments they used in the past (such as medicines or therapies), how long they used them, and whether these treatments helped their symptoms.
This is a non-interventional study, which means no new treatments will be given and no changes will be made to patient care. The study will simply collect information about past experiences. All participants will provide informed consent, and their personal data will be kept confidential.
The results will help researchers better understand real-world treatment patterns and how patients respond to different therapies, which may support future research and improve care for people with chronic cough.REC name
West of Scotland REC 3
REC reference
26/WS/0113
Date of REC Opinion
9 Jul 2026
REC opinion
Favourable Opinion