Group ACT for CD pain V1.0

• Research type

  Research Study

• Full title

  Managing pain in people with Crohn's Disease: Feasibility Testing of an Acceptance and Commitment Group Therapy intervention.

• IRAS ID

  314107

• Contact name

  Natalie Watson

• Contact email

  Natalie.1.watson@kcl.ac.uk

• Sponsor organisation

  King's College London

• Clinicaltrials.gov Identifier

  NCT05418062

• Duration of Study in the UK

  2 years, 0 months, 0 days

• Research summary

  Pain is a common symptom of inflammatory bowel disease (IBD) and has a significant impact on patient quality of life. Pain will frequently be the presenting complaint and is experienced throughout the disease course. Up to 70% of patients experience pain in active disease, and up to half (20-50%) of patients will experience pain in remission.
  Pain in IBD is widely recognised as a biopsychosocial construct, with visceral hypersensitivity, as well as depressive symptoms, anxiety, stress and fear avoidance correlating positively with IBD-pain. There is increasing understanding of the psychological interaction and need for psychological management within IBD. Psychological therapies such as Cognitive Behavioural Therapy (CBT) and acceptance and commitment therapy (ACT) have been used widely in other conditions, such as chronic pain, fatigue and irritable bowel syndrome (IBS).

  Although neither ACT nor CBT have been used specifically for pain in IBD, ACT has become a regular therapy in the management of chronic pain and a large number of studies have found it to be effective, particularly in relation to improving functioning and decreasing distress, quality of life and physical wellbeing.

  This study design is a crossover randomised controlled trial of ACT versus treatment-as-usual (TAU) in people with CD and chronic abdominal pain. We aim to assess the feasibility of ACT for reducing the impact of abdominal pain and its associated psychological burden in people with Crohn’s disease (CD). The study will investigate the acceptability of ACT to people with CD and chronic pain, specifically testing issues of eligibility, recruitment, retention rates, patient experience and performance of proposed outcome measures. This will inform the design of a subsequent large multi-centre randomised controlled trial (RCT) with long-term follow-up.
  

• REC name

  London - City & East Research Ethics Committee

• REC reference

  22/LO/0574

• Date of REC Opinion

  5 Sep 2022

• REC opinion

  Favourable Opinion