GPAMS

  • Research type

    Research Study

  • Full title

    Global Polar and Altitude Metabolism Study

  • IRAS ID

    273397

  • Contact name

    Chris Imray

  • Contact email

    Christopher.Imray@uhcw.nhs.uk

  • Sponsor organisation

    Research and Development,

  • Duration of Study in the UK

    2 years, 4 months, 31 days

  • Research summary

    When the first Arctic explorers breached its terrain, the knowledge of human physiology responses to this extreme environment was minimal. While today, there is still much to learn, our understanding is much better as a result of years of research pioneered by physiologists interested in exploring the extreme and fascinating effects of these environments on human physiology.
    However, at present the research interest have broadened and a new paradigm suggests physiological and pathophysiological responses to extreme environmental challenges (for e.g. hypoxia, cold, heat, microgravity) may be similar to those experienced by patients in critical care (1,2). Thus an expedition in Polar and High altitude environments provides us with the unique opportunity to explore human physiological responses in an exciting natural laboratory for translational medical research. The purpose of this study is to map human physiological and metabolic responses when exposed to these conditions using the latest technology, which may help in exploring the pathophysiology of critical illness.

  • REC name

    West Midlands - Black Country Research Ethics Committee

  • REC reference

    19/WM/0330

  • Date of REC Opinion

    13 Dec 2019

  • REC opinion

    Further Information Favourable Opinion