GlyCarb Remote
Research type
Research Study
Full title
Measuring postprandial Glycaemic responses to Carbohydrate-rich meals using a standardised remote monitoring protocol
IRAS ID
300090
Contact name
Cathrina Edwards
Contact email
Sponsor organisation
Quadram Institute bioscience
Duration of Study in the UK
1 years, 4 months, 28 days
Research summary
Carbohydrate-based foods such as potatoes, bread, rice, pasta, breakfast cereals, biscuits and other snacks are a big part of the human diet, but large intakes of carbohydrate cause large blood sugar excursions which, over time, can be detrimental for human health as they increase risk of developing type 2 diabetes.
The aim of the GlyCarb study is to investigate how food properties (food structure) influence postprandial glycaemic responses to carbohydrate foods.
This will be achieved through a series of acute postprandial studies (up to 5 studies), wherein healthy participants consume a set of carbohydrate-rich test meals while wearing a continuous glucose monitoring system (CGM).
Each postprandial study will use the same GlyCarb Remote standard protocol, where a randomised cross-over design is used to measure the glycaemic response to two carbohydrate-rich test meals, one “test” and one “control”. Both meals will be matched by carbohydrate content, contain similar ingredients and have a similar physical appearance, but will differ in one key food property (e.g., altered food structure) to test its effect on postprandial glycaemia. The meals will be well characterised and details of nutrient composition, ingredients, allergens etc. will be provided to participants prior to consent. The study population will be healthy participants access to a smart phone to be used in conjunction with the CGM as well as for virtual study appointments (video call) and to complete online forms.REC name
East of England - Cambridge South Research Ethics Committee
REC reference
21/EE/0245
Date of REC Opinion
9 Nov 2021
REC opinion
Favourable Opinion