GlobalMinds
Research type
Research Study
Full title
GlobalMinds: Development of an internationally-diverse, linked genomic and longitudinal phenotypic research data asset to accelerate precision treatment pathways for patients with serious mental illness
IRAS ID
328854
Contact name
James Walters
Contact email
Sponsor organisation
Akrivia Health
Duration of Study in the UK
3 years, 6 months, 4 days
Research summary
Akrivia Health wish to understand the links between both mental illnesses and dementias with human biology, and better understand the experiences of people with these conditions. In this study we will focus on recruiting people with diagnoses of psychotic or mood disorders, as well as people with dementias. This study aims to provide new insights into the nature and classification of severe mental illness and dementias that in time should help improve diagnostic practise, and enable the development of new and improved treatments.We will achieve our aims this by gathering information and biological samples from over 50,000 research participants and then linking this information with participants’ electronic health records, genetic and other potential markers of mental illnesses (called biomarkers, derived from biological samples). We will use this resource to analyse how potential risk factors - genetic, other biological and non-biological (related to the participants’ life circumstances) - influence participants’ experiences, symptoms, and outcomes (both mental and physical health). We will also use advanced analysis to assess whether there may be better ways of grouping together and understanding the experiences of those with severe mental illnesses and dementias. Given the value and importance of this resource for advancing mental health research we will also make the data available to other researchers to pursue these broad research aims.
REC name
Wales REC 2
REC reference
24/WA/0299
Date of REC Opinion
27 Nov 2024
REC opinion
Further Information Favourable Opinion