Glasgow Traumatic Brain Injury Archive
Research type
Research Tissue Bank
IRAS ID
320886
Research summary
Glasgow Traumatic Brain Injury Archive: A satellite collection under
the governance of the NHS Greater Glasgow & Clyde Bio-repositoryREC name
West of Scotland REC 1
REC reference
22/WS/0168
Date of REC Opinion
29 Dec 2022
REC opinion
Further Information Favourable Opinion
Data collection arrangements
The Glasgow TBI Archive will house a register of prospective tissue donors who wish to gift their tissue for medical research in the event of their death. In keeping with local/national autopsy authorisation procedures, the next of kin will give their formal authorisation (consent) for a post mortem examination to be carried out and for tissue to be collected for future medical research purposes at the time of death. All tissue collected will be stored under the auspices of the GGC Bio-repository who will also be responsible for the governance and access to the banked samples
Research programme
The proposed extension of current favourable ethical approval is intended to address the continued need for suitable human tissue to support national and international research studies directed towards understanding the neuropathological consequences of survival from traumatic brain injury (TBI). Currently, only one comprehensive research archive of human tissues to support studies in TBI exists internationally, the Glasgow TBI Archive. Our and others' recent studies in this field have shown complex and evolving pathologies in survivors of TBI which might contribute to the recognised increased risk of dementia in this population; an issue attracting considerable attention in the media at present through the proposed link between sports brain injury and dementia. Since inception of the current research tissue registration and donation programme, the Glasgow TBI Archive's global leadership in this field has continued to evolve, with this archive now leading an international, multi-centre collaboration facilitating access to human tissue samples for research in TBI, the "COllaborative Neuropathology NEtwork Characterising ouTcomes from TBI (CONNECT-TBI)", and supporting multiple national and international research programmes.
RTBTitle
Glasgow Traumatic Brain Injury Archive: A satellite collection under the governance of the NHS Greater Glasgow & Clyde Bio-repository
Establishment organisation
NHS Greater Glasgow and Clyde
Establishment organisation address
Neuropathology Research Laboratory
Level 2, Laboratory Medicine Building
Queen Elizabeth University Hospital
G514TF