GIFT-Surg - Fetal USS
Research type
Research Study
Full title
Fetal ultrasound and fetal monitoring technologies to improve prenatal diagnosis and therapy for fetal abnormality and maternal and fetal perinatal outcome
IRAS ID
230125
Contact name
Raffaele Napolitano
Contact email
Sponsor organisation
Joint Research Office, University College London
Clinicaltrials.gov Identifier
Z6364106/2019/01/24, UCL Data Protection Office Registration
Duration of Study in the UK
10 years, 0 months, 1 days
Research summary
Guided Instrumentation for Fetal Therapy and Surgery is a seven-year project funded by the Wellcome Trust and Engineering and Physical Sciences Research Council (EPSRC). In collaboration with KU Leuven, Great Ormond Street Hospital and University College Hospital (UCLH) we aim to develop low-risk techniques for diagnosis and treatment of a range of debilitating abnormalities of the baby during pregnancy and before birth.
In order to improve diagnosis of fetal abnormality and wellbeing we have set up a study investigating ultrasound imaging and computerised Cardiotocography (CCTG). We will invite women seen in the Integrated Antenatal Services at University College London Hospital for additional ultrasound imaging or CCTG monitoring of the fetal heart beat. The aim of this study is to improve prenatal diagnosis and therapy for fetal abnormality by:
• Understanding the ability and limitations of 2D, 3D, 4D and Doppler ultrasound and CCTG, to visualise fetal and pregnancy structures and function.
• Understanding the natural history of pathologies, helping to inform how cases should be managed – such as when to offer intervention, delivery, or termination of pregnancy.
• Developing novel post-processing algorithms that will improve the information available to the clinician from ultrasound imaging and related ultrasound-based imaging such as CCTG.REC name
North of Scotland Research Ethics Committee 2
REC reference
19/NS/0053
Date of REC Opinion
17 Apr 2019
REC opinion
Further Information Favourable Opinion