Genetic influence on outcome after brain haemorrhage
Research type
Research Study
Full title
Genetic influence on outcome after brain haemorrhage
IRAS ID
270207
Contact name
I Galea
Contact email
Sponsor organisation
University of Southampton
Clinicaltrials.gov Identifier
49253.A1, ERGO II
Duration of Study in the UK
5 years, 0 months, 1 days
Research summary
Bleeding into the brain, or brain haemorrhage, leaves the individual with significant life-changing effects, but this varies from one individual to the other, even though the haemorrhage may be of the same size. This suggests that there are genetic factors which impact on clinical outcome after brain haemorrhage. Identification of these genetic factors will result in new ways of predicting clinical outcome after brain haemorrhage and devising new treatments. In this study, we will analyse acellular DNA samples and genetic data from patients with brain haemorrhage and correlate this with clinical outcome. Fully anonymized DNA samples, genetic and clinical data will come from two studies, representing the two main types of brain haemorrhage: the GOSH study recruited patients with subarachnoid haemorrhage while the CROMIS-II study recruited patients with intracerebral haemorrhage.
REC name
South Central - Berkshire Research Ethics Committee
REC reference
19/SC/0485
Date of REC Opinion
28 Aug 2019
REC opinion
Favourable Opinion