Genetic analysis of primary rhegmatogenous retinal detachment
Research type
Research Study
Full title
Case-control genetic association analysis of primary rhegmatogenous retinal detachment using novel high density exome genotyping
IRAS ID
113702
Contact name
David Charteris
Contact email
Sponsor organisation
Moorfields Eye Hospital
Research summary
Retinal detachment is a common eye condition that can result in blindness. Although treatments are available, the exact cause of t his condition is not known. We plan to perform a large scale gene tic study on retinal detachment to try and discover genes which p redispose to this condition. To do this, we will perform a genetic scan of people who have had a retinal detachment and compare this to a similar group of people who have never had a retinal detachment. We hope this research will provide us with new information about the underlying gene tics of retinal detachment and give us a better idea of what biological mechanisms cause this condition, so that we can develop improved ways to treat or prevent it.
We will enrol 500 patients into this study. Only a blood test is required. No extra clinical testing will be done for the purposes of this study.
This study is sponsored by Moorfields Eye Hospital and is funded b y the Special Trustees of Moorfields Eye Hospital and the Biomedical Research Centre for Ophthalmology and Royal College of Surgeons of Edinburgh.REC name
London - Camden & Kings Cross Research Ethics Committee
REC reference
13/LO/0358
Date of REC Opinion
5 Jun 2013
REC opinion
Further Information Favourable Opinion