geko® T3 One vs Two Study

  • Research type

    Research Study

  • Full title

    Exploring Haemodynamic Effects of Unilateral vs Bilateral NMES of the Lower Limb Using the geko® T3 Device in Healthy Volunteers

  • IRAS ID

    365185

  • Contact name

    Kieron Day

  • Contact email

    kieron.day@firstkindmedical.com

  • Sponsor organisation

    Firstkind Ltd

  • Duration of Study in the UK

    0 years, 0 months, 26 days

  • Research summary

    This study will explore how blood flow in the legs changes when a small, wearable medical device called the geko® T3 is used on one leg compared to both legs at the same time. The geko® device delivers gentle electrical pulses to a nerve just below the knee, which causes the muscles in the lower leg to contract slightly. These contractions help to improve blood circulation, similar to how movement or walking encourages blood flow.

    The geko® T3 is already approved for use in the UK (UKCA and CE marked) to help increase blood flow in the lower limbs. However, most studies so far have only tested it on one leg at a time. This study will compare the effects of using the device on one leg (unilateral stimulation) and both legs (bilateral stimulation) in healthy adult volunteers. Understanding these effects will help researchers to optimise future use of the device in both clinical and everyday settings.

    Six healthy volunteers aged 18 years or older will take part. Each person will attend one study visit lasting about two and a half hours. During the visit, ultrasound measurements will be used to record blood flow in the legs at rest, with one device applied, and with two devices applied.

    The geko® device is non-invasive and low risk. Some people may feel mild tingling or temporary muscle twitching during stimulation, but no harmful effects are expected. Participants will be closely monitored throughout the study.

    Although there is no direct benefit to participants, the results will help to improve understanding of how this technology supports blood circulation and inform future research.

  • REC name

    North East - Newcastle & North Tyneside 2 Research Ethics Committee

  • REC reference

    25/NE/0226

  • Date of REC Opinion

    3 Dec 2025

  • REC opinion

    Further Information Favourable Opinion