FOLLOW-COVID
Research type
Research Study
Full title
FOcused LongitudinaL Observational study to improve knoWledge of COVID-19
IRAS ID
284116
Contact name
David Connell
Contact email
Sponsor organisation
NHS Tayside
ISRCTN Number
ISRCTN76339681
Duration of Study in the UK
6 years, 0 months, 1 days
Research summary
Background: Severe COVID-19 infection can cause severe pneumonia and acute respiratory distress syndrome (ARDS) leading to a requirement for mechanical ventilation. It is also now recognised that it can cause inflammation of blood vessels which may lead to a longer term increased risk of cardiovascular disease. NHS Scotland must plan for the long term care of potentially thousands of patients who will experience long term complications of COVID-19, both within the lung and outside the lung. As COVID19 is a new disease, there is a need to identify the long term consequences and future care needs of COVID19 survivors.
Eligibility: We wish to establish a national cohort of 300 people with COVID19.
Outcomes: In this study we will use blood testing, urine, respiratory samples, and tests of blood vessel function to help determine the long term consequences of this disease and identify future management approaches. This will be through the current study and in the future with analysis of healthcare use.
Specific interests will include the recovering epithelial function in the lungs; endothelial function relating to cardiovascular disease and diabetes; effects of COVID-19 on complications related to, and management of diabetes; characterising the microbiome of the airway epithelium after COVID-19; development of a biobank of samples to further research predictors of long term health outcomes; long term assessment of healthcare use following COVID disease.
REC name
Yorkshire & The Humber - South Yorkshire Research Ethics Committee
REC reference
20/YH/0265
Date of REC Opinion
16 Sep 2020
REC opinion
Further Information Favourable Opinion