Flow variations through Continuous Flow Ventricular Assist Devices
Research type
Research Study
Full title
Left Ventricular Contraction Induced Flow Variations through Continuous Flow Left Ventricular Assist Devices and Exercise Capacity
IRAS ID
171414
Contact name
Guy MacGowan
Contact email
Sponsor organisation
Newcastle upon Tyne NHS Foundation Trust
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
Left ventricular assist devices (VAD) are mechanical pumps inserted into the left ventricle of patients with end-stage heart failure to restore the circulation. These patients are expected to regain a near normal quality of life, though some patients are able to perform daily activities better than others. We propose to use a monitor that is attached to the controller of the VAD that can assess the beat to beat variations in flow through the device. These variations are due to contraction of the left ventricle, which although weak, can augment the flow through the device. We will test the hypothesis that the greater the degree of these flow variations through the device result in an improved overall functional activity.
REC name
East of England - Cambridge Central Research Ethics Committee
REC reference
15/EE/0183
Date of REC Opinion
11 May 2015
REC opinion
Further Information Favourable Opinion