FLIPPer Study, 3.0
Research type
Research Study
Full title
Family Life Impacts of Paediatric Respiratory Papillomatosis study
IRAS ID
350122
Contact name
Daniel Hawcutt
Contact email
Sponsor organisation
University of Liverpool
Duration of Study in the UK
0 years, 4 months, 18 days
Research summary
Recurrent Respiratory Papillomatosis is a rare, chronic condition, caused by the Human Papillomavirus, mainly types 6 and 11. It is characterised by recurrent warts/papillomas which grow along the respiratory tract, and can cause hoarseness, stridor and airway obstruction. Unfortunately, there is no cure, and patients often require repeated surgeries to remove the papillomas. It affects both adults and children, though the childhood disease is often more aggressive and likely to recur post treatment. Existing research mainly focuses on the efficacy of treatment options, though recent research has started to look at the quality of life (QoL) of these patients. This new qualitative research has mainly been produced through the use of surveys capturing specific points, instead of exploring the broader impacts of the condition. Additionally, it is often focused on adults with the condition, despite the condition being worse in children, and having a larger impact on the families due to the lack of independence of the children. This has left a gap in the knowledge surrounding the wider impact that a chronic condition like RRP can have on the patient and family. The FLIPPer study aims to address this gap, by exploring the familial perspective of this condition and its impact, through a narrative style interview and thematic analysis. From this, we hope to enhance the service delivery and support that we are able to provide to patients and families with the condition.
REC name
London - Chelsea Research Ethics Committee
REC reference
25/PR/0057
Date of REC Opinion
12 Feb 2025
REC opinion
Further Information Favourable Opinion