FLiP-GD2
Research type
Research Study
Full title
Is Fat in the Liver a marker of post-Pregnancy Glycaemic Deterioration in women with Gestational Diabetes?
IRAS ID
214643
Contact name
Fahmy Hanna
Contact email
Sponsor organisation
University Hospitals of North Midlands NHS Trust
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
Gestational diabetes mellitus (GDM) is diabetes detected for the first time during pregnancy. After delivery, it usually resolves. However, 50-70% of patients ultimately develop diabetes within 10 years. Therefore, detecting GDM is not only important for safe delivery but also it identifies women at risk of having diabetes later, in order to start diet and exercise to prevent diabetes. Research confirms that these are very effective in preventing diabetes.\n\nFat in in the liver that is not related to excess alcohol (Non-Alcoholic Fatty Liver Disease; “NAFLD“) is well established as another important risk factor for future development of diabetes. This can be detected in routine practice by ultrasound scan or by the Fatty Liver Index (FLI) scoring system (including simple blood tests together with the patient’s height, weight and waist circumference).\n\nWe propose to check for fat in the liver in GDM patients and if detected it could identify those with the highest risk for developing diabetes. This would allow the future use of individualised treatment to prevent or delay onset of diabetes in these young women.
REC name
North West - Greater Manchester South Research Ethics Committee
REC reference
17/NW/0015
Date of REC Opinion
4 Apr 2017
REC opinion
Further Information Favourable Opinion