FIORELLO: Finerenone in paediatric heart failure patients with left ventricular systolic dysfunction

• Research type

  Research Study

• Full title

  A Phase 3, single-arm, open-label extension study to evaluate the safety of finerenone in addition to standard of care, in pediatric heart failure patients, from birth to 18 years of age, with left ventricular systolic dysfunction (LVSD)

• IRAS ID

  1012289

• Contact name

  Abbas Khushnood

• Contact email

  a.khushnood@nhs.net

• Sponsor organisation

  Bayer AG

• Research summary

  A study to learn more about how safe finerenone is, when it is taken for a longer time with standard treatment, in children and young adults with heart failure and left ventricular systolic dysfunction.

• REC name

  North of Scotland Research Ethics Committee 1

• REC reference

  25/NS/0091

• Date of REC Opinion

  30 Sep 2025

• REC opinion

  Further Information Favourable Opinion