FFC-MRI in brain lesions
Research type
Research Study
Full title
Non-invasive in-vivo characterisation of brain lesions using Fast Field Cycling Magnetic Resonance Imaging (FFC-MRI)
IRAS ID
241397
Contact name
Arnab Rana
Contact email
Sponsor organisation
University of Aberdeen and NHS Grampian
Duration of Study in the UK
1 years, 9 months, 31 days
Research summary
Summary of Research
Fast Field Cycling MRI (FFC MRI) is a new scanning technology which is being developed at the University of Aberdeen. Previous pilot studies by our team on osteoarthritis, breast cancer, musculoskeletal cancer, liver fibrosis, thrombosis and muscle damage have demonstrated that FFC MRI provides useful information for clinical diagnostics in a variety of pathologies.
The aim of this study is to observe brain lesions with Fast Field Cycling MRI to discover differences in the signal given by various types of brain lesions.
Summary of Results
This study successfully scanned ten patients with suspected meningiomas and diffuse gliomas prior to surgery. Scanning with the experimental Field Cycling Imaging (FCI) technique was performed 01/05/2019 and 29/02/2024. Six patient had suspected gliomas and four patients had suspected meningiomas.
Measurements using FCI have been made of the tumour areas and corresponding normal brain areas. We have prepared these for publication to the scientific community. These will be presented at the International Society for Magnetic Resonance in Medicine in May 2025.
REC name
North of Scotland Research Ethics Committee 1
REC reference
19/NS/0033
Date of REC Opinion
4 Apr 2019
REC opinion
Further Information Favourable Opinion