Fetal Atrial Flutter & Supraventricular Tachycardia Therapy Trial

• Research type

  Research Study

• Full title

  Fetal Atrial Flutter & Supraventricular Tachycardia (FAST) Therapy Trial

• IRAS ID

  196628

• Contact name

  Julene Carvalho

• Contact email

  JCARVALH@SGUL.AC.UK

• Sponsor organisation

  St Georges University Hospital NHS Foundation Trust

• Eudract number

  2015-005743-14

• Clinicaltrials.gov Identifier

  NCT02624765

• Duration of Study in the UK

  4 years, 11 months, 31 days

• Research summary

  Pregnancies can be complicated by an abnormally fast heart rate up to 300 beats per minute due to supra-ventricular tachyarrhythmia (SVA) in the unborn baby (foetus)This carries significant risks because the baby can tolerate fast heart rates only for a short period before heart failure, shock or even death occurs. Premature delivery and perinatal death are frequent adverse outcomes of babies with heart failure and uncontrolled SVA before birth. Treatment is offered to most mothers to normalize the foetal heart rate to prevent or treat foetal heart failure and to continue pregnancy to term with a normal delivery. The FAST Therapy Trial aims to determine the efficacy and safety of standard drug regimens for fetal SVA.

• REC name

  London - Hampstead Research Ethics Committee

• REC reference

  16/LO/0251

• Date of REC Opinion

  21 Mar 2016

• REC opinion

  Further Information Favourable Opinion