Feasibility study to support medication adherence following ACS
Research type
Research Study
Full title
The development, feasibility and acceptability of a hospital-based intervention to support medication adherence following acute coronary syndrome
IRAS ID
212827
Contact name
John Weinman
Contact email
Sponsor organisation
King's College London
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 2 months, 30 days
Research summary
Background
Medication adherence following acute coronary syndrome (ACS) is often sub-optimal and is associated with poor clinical outcomes. There is evidence that psychosocial factors such as treatment beliefs play a role in determining adherence (Crawshaw et al., 2016) and have the potential to be changed through intervention (Johnston et al., 2016).Aims
The aim of this proposed study is to determine the feasibility of a hospital-based intervention to support medication adherence in patients following ACS.Methods
Patients diagnosed with ACS will be recruited from a single NHS site. The intervention will challenge both perceptual and practical barriers to adherence during two hospital-based sessions with a study researcher. The first session will focus on treatment beliefs and challenge any misconceptions patients have about their medications. The second session will involve formulating action plans to help patients establish a clear medication-taking routine for when they return home.Outcomes
The outcome of this study is its feasibility and acceptability to patients. Feedback will be gathered around the setting, timing, content and delivery method of the intervention. Feedback will be gathered at two time points - immediately after the intervention has been completed in hospital and 2-3 weeks after discharge.Crawshaw J, Auyeung V, Norton S, Weinman J. Identifying psychosocial predictors of medication non-adherence following acute coronary syndrome: A systematic review and meta-analysis. Journal of Psychosomatic Research. 2016 Nov 30;90:10-32.
Johnston N, Weinman J, Ashworth L, Smethurst P, El Khoury J, Moloney C. Systematic reviews: causes of non-adherence to P2Y12 inhibitors in acute coronary syndromes and response to intervention. Open Heart. 2016 Oct 1;3(2):e000479.
REC name
London - Chelsea Research Ethics Committee
REC reference
17/LO/0050
Date of REC Opinion
13 Feb 2017
REC opinion
Further Information Favourable Opinion