Feasibility & Acceptability of an Intervention to Prevent MLTCs

  • Research type

    Research Study

  • Full title

    Exploring the most feasible and acceptable way of providing an intervention to prevent Multiple Long Term Conditions

  • IRAS ID

    362782

  • Contact name

    Katherine Bradbury

  • Contact email

    kjb1e08@soton.ac.uk

  • Sponsor organisation

    University of Southampton

  • Clinicaltrials.gov Identifier

    70900, Central Portfolio Management System

  • Duration of Study in the UK

    1 years, 6 months, 1 days

  • Research summary

    This qualitative study aims to explore patient, healthcare practitioner and policymaker views on how we might best prevent multiple long term conditions. This study forms part of a larger NIHR programme grant. The first part of this grant is separate to this application and uses epidemiology work, which is underway to identify who is most at risk of developing multiple long term conditions (MLTCs). The epidemiology work will also develop the final list of possible medication changes that would be useful in preventing MLTCs. This would be a similar approach to the electronic frailty index currently used in primary care.

    The current project which we seek ethical approval for will run after this epidemiology work. The question the current project aims to address is what should be done once people are identified as high risk of developing multiple longterm conditions? We wish to co-design an approach to support people to lower their risk of developing MLTCs and this study aims to explore what patients, healthcare practitioners and policy makers think would be appropriate ways that primary care could support those at high risk to make the necessary changes to lower their risk factors, using qualitative research. Risk factors are likely to be things such as lifestyle changes (e.g. dietary changes, weight loss, increasing physical activity), changing certain medications that increase risk of multimorbidity or adding medications that reduce this risk (such as anti-inflammatories).

    The qualitative work contains two studies, which will run concurrently.
    Study 1 explores what is feasible and acceptable to healthcare practitioners and policy makers in providing support to patients for preventing MLTCs within primary care.

    Study 2 explores how patients feel they can be best supported to make changes to the identified risk factors.


  • REC name

    South Central - Berkshire Research Ethics Committee

  • REC reference

    26/SC/0027

  • Date of REC Opinion

    23 Feb 2026

  • REC opinion

    Favourable Opinion