Factors affecting adherence to guideline recommended treatment in PAD
Research type
Research Study
Full title
Barriers and facilitators to adherence to guideline-recommended treatment in patients with peripheral artery disease
IRAS ID
300326
Contact name
Mary Wells
Contact email
Sponsor organisation
Research Governance and Integrity
Clinicaltrials.gov Identifier
NIHR301947, NIHR PCAF
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
Peripheral arterial disease (PAD) is an illness that affects one in five people aged over 60 in the UK. Arteries carry blood from the heart to the body. When fat builds up inside the arteries it can cause blockages that reduce blood supply in the legs. As a result, patients can suffer from pain while walking. When left untreated it can also lead to a heart attack, stroke and increased risk of death. In addition, 4-27% of patients with this condition will lose their legs within six years.
The National Institute of Health and Care Excellence suggests four non-surgical treatments that aim to help these patients manage their disease. This includes cholesterol-lowering and blood-thinning tablets; regular exercise and stopping smoking. Unfortunately, patients do not always follow their treatment plan. This can be difficult for healthcare professionals to manage as there are currently no studies that explore how well patients follow all four PAD treatment options. Existing work shows that family and friends play an important role in supporting patients to manage health conditions. However, little is known about their role in supporting patients with PAD.
This study will find out how well patients follow the therapies recommended by their health care provider. It will also explore which factors influence patient decisions, such as the impact of their family and friends. Patients with PAD who attend the Imperial College Healthcare NHS Trust Vascular Clinics will complete a survey. This will help find out how many patients follow their treatment plan and what factors influence their decisions. Some patients and their families and friends will also take part in interviews to learn more about these factors.
It is important to fully understand the factors that affect the way PAD patients follow their treatment plan. The results will help healthcare professionals to offer more tailored care for PAD patients and give PAD patients a chance for a better quality of life.REC name
London - Harrow Research Ethics Committee
REC reference
21/PR/1459
Date of REC Opinion
2 Dec 2021
REC opinion
Further Information Favourable Opinion