Eyelid Melanoma and version 1.2
Research type
Research Study
Full title
The Incidence and epidemiology of Eyelid Melanoma in the UK
IRAS ID
252915
Contact name
John Bladen
Contact email
Sponsor organisation
Kings College Hospital NHS Foundation Trust
Duration of Study in the UK
1 years, 10 months, 1 days
Research summary
The incidence of malignant eyelid melanoma is unknown along with its clinical, visual, histological, genomic and prognostic characteristics. Anecdotal evidence suggests that the eyelid is a high-risk region and more understanding of this visually threatening disease is required. We aim to establish a current incidence rate for eyelid melanoma using an epidemiological (prospective population-based) study using the British Ophthalmological Surveillance Unit (BOSU) monthly reporting card scheme. This is an active surveillance system involving all UK ophthalmologists with clinical autonomy (consultant and associate specialist grade). The study uses only information available from the patient case notes.
Ophthalmologists will indicate that they have seen a new eyelid melanoma case through the BOSU. The BOSU collects no patient identifying information but will notify the study investigator (Dr John Bladen) of all ophthalmologists who report new cases. The researcher will then contact the reporting ophthalmologist directly and will be sent a questionnaire requesting information to determine the incidence, but also secondary aims of histological subtype, the treatment given, prognosis and the effect on vision.
Research analysis will be carried out at one site at Kings College Hospital (Princess Royal University Hospital (PRUH)). No procedures mentioned in the Standard Operating Procedures for ethics committees in the United Kingdom will be carried out which require a principal investigator to be appointed at each site. Analysis will be descriptive and all findings reported in an aggregated format and at no point will the patient’s routine standard care be altered or impacted as a result of this study.
REC name
London - London Bridge Research Ethics Committee
REC reference
19/LO/0862
Date of REC Opinion
4 Jun 2019
REC opinion
Favourable Opinion