Extraction of DNA from whole blood and bone marrow aspirate

• Research type

  Research Study

• Full title

  Extraction of DNA from whole blood and bone marrow aspirates for use with an IDH detection qPCR kit in development

• IRAS ID

  315013

• Contact name

  Nathan Dennison

• Contact email

  Nathan.Dennison@qiagen.com

• Sponsor organisation

  QIAGEN

• Duration of Study in the UK

  2 years, 6 months, 1 days

• Research summary

  DNA will be extracted from whole blood and bone marrow aspirates collected in K2-EDTA tubes. The samples have been collected from healthy patients and patients diagnosed with either Acute Myeloid Leukaemia (AML) or Myelodysplastic Syndrome (MDS). The DNA will be extracted from both fresh and frozen samples. The extracted DNA will be used in feasibility and development assessments of an IDH mutation detecting qPCR assay.

• REC name

  HSC REC B

• REC reference

  22/NI/0187

• Date of REC Opinion

  20 Dec 2022

• REC opinion

  Further Information Favourable Opinion