Exploring Quality of Life Markers after IV Iron in Perinatal Women
Research type
Research Study
Full title
Exploring the Impact of Intravenous Iron on Quality of Life Indicators in the Perinatal Period
IRAS ID
232662
Contact name
Sue Pavord
Contact email
Sponsor organisation
Oxford Brookes university
Duration of Study in the UK
0 years, 5 months, 14 days
Research summary
The study seeks to explore the impact of intravenous iron (ferric carboxymaltose) on maternal quality of life in pregnant and postnatal women with iron deficient anaemia.
I aim to recruit 40 women, with a clinical need for intravenous iron between 24-38 weeks gestation, or women who have given birth in the last two weeks. After written, informed consent, they will be invited to complete two questionnaires concerning health related quality of life: SF-36 and Wolverhampton. These questionnaires will be repeated at 2 and 4 week intervals after the infusion. Qualitative interviews will enable questionnaire responses to be explored in greater depth. Recruitment to the interview stage will stop after data saturation has been achieved (approximately 10 to 20 interviews).
The results will be used to inform my masters dissertation and add to the research surrounding the efficacy of intravenous iron. Previous research has demonstrated superiority of intravenous iron over an oral regime in relation to the improvement of haemoglobin levels (Seid, 2008; Van Wyk, 2007; Breymann, 2016; Breymann, 2008). The majority of this research, however, does not report on women's quality of life improvements after iron therapy in adequate depth, despite the adverse side of effects of iron therapy being well documented (Markova, 2015; Reveiz, 2011). Therefore it is unknown how IV iron impacts on women's lives, in regards to their overall wellbeing, and symptoms of anaemia and subsequent treatment. A mixed methods study with a primary outcome of quality of life indicators, will contribute to the existing research on the efficacy of treatments for iron deficient anaemia in pregnant and postnatal women.
REC name
Yorkshire & The Humber - Leeds West Research Ethics Committee
REC reference
17/YH/0408
Date of REC Opinion
27 Nov 2017
REC opinion
Favourable Opinion