Exploring Context Change Study
Research type
Research Study
Full title
Context change and effects on nebuliser adherence among people with cystic fibrosis
IRAS ID
178505
Contact name
Zhe Hui Hoo
Contact email
Sponsor organisation
Sheffield Teaching Hospitals NHS Foundation Trust
Duration of Study in the UK
2 years, 6 months, 27 days
Research summary
Cystic Fibrosis (CF) is a lifelong condition which causes the lungs and digestive system to become clogged with thick, sticky mucus. This leads to recurrent lung infections and reduced nutrient absorption from food. The average age at death is 26 years, usually from respiratory failure. People with CF can benefit from a variety of maintenance treatments to keep them healthy, by preventing infection and maintaining a good weight. However treatment is burdensome and unsurprisingly adherence to those treatments is often poor.
Adolescence can be a challenging period whereby people experience rapid social, physical and psychological changes. Adherence to treatment is particularly poor during adolescence, which is associated with more rapid drop in lung function compared to other periods. This study aims to learn how habit and the behaviour of using nebuliser change with time during this crucial period.
We aim to recruit 15 participants. Data will be collected over a 12-month period, so that we can analyse the patterns of change.
Participants' adherence data and prescription details will be collected. Participants will be invited to answer an online questionnaire every month. We also plan to do between 3 and 5 interviews for each participant during the study period.
The changes experienced by participants, and the adaptations they made to continue using their nebuliser will be identified from the interviews. Habit strengths and other factors that influence behaviour will be obtained from the questionnaires.
REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
15/YH/0144
Date of REC Opinion
14 Apr 2015
REC opinion
Favourable Opinion