Exploration of investigating ICU mobilisation with vasoactive drugs v1
Research type
Research Study
Full title
Investigating the safety of mobilising intensive care unit patients receiving vasoactive drugs: An exploratory observational study
IRAS ID
251112
Contact name
Anthony Gordon
Contact email
Sponsor organisation
Imperial College London
Duration of Study in the UK
0 years, 6 months, 31 days
Research summary
An exploration of investigating the safety of mobilising intensive care patients receiving vasoactive drugs.
There is evidence that getting patients out of bed and walking (mobilisation) on an intensive care unit (ICU) can help reduce the substantial physical problems experienced by ICU survivors. A vital safety factor for mobilisation is poor heart system function requiring vasoactive drugs (medication to support the heart and blood pressure). We need to know more about the safety of mobilising patients who are receiving these vasoactive drugs. But before we can do this research, several uncertainties need to be addressed.
To answer these uncertainties, we will ask 40 ICU patients receiving vasoactive drugs to take part in a study in three main stages. Firstly we will ask the ICU patients whether they would be happy to take part in a future research trial on the safety of mobilising patients who are receiving vasoactive drugs. We would also check with clinicians that it would be acceptable to them. Secondly, we will collect data about the current mobilisation on vasoactive drugs that occurs. This includes measuring any unsafe events that occur. Finally, we will see if we can follow up these patients 60 days after they start the study, to carry out some questionnaires and a walking test with the patients. These tests may be used in future research to measure the effect of mobilising patients on vasoactive drugs.
This study is funded as part of a National Institute for Health Research Clinical Doctoral Research Fellowship.
REC name
Wales REC 6
REC reference
18/WA/0310
Date of REC Opinion
17 Oct 2018
REC opinion
Further Information Favourable Opinion