ExoChase Study
Research type
Research Study
Full title
Identification of Blood Biomarkers for Antenatal Diagnosis of Congenital Heart Disease
IRAS ID
283775
Contact name
Iain Dykes
Contact email
Sponsor organisation
Liverpool John Moores University
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
Congenital Heart Disease (CHD) is the most common type of birth defect worldwide. It affects around 8 in every 1,000 babies born in the UK. Many of these babies require surgical correction, which is why it is important to diagnose CHD as early as possible, allowing parents to make better informed decisions and resulting in better clinical outcomes. It has been suggested, that the baby releases specific biological molecules, which can be detected in the mother’s blood and provide information about the baby’s heart development. This study hopes to identify these molecules in order to create a simple blood test by which babies with CHD can be easily screened or diagnosed.
REC name
East of Scotland Research Ethics Service REC 1
REC reference
20/ES/0123
Date of REC Opinion
8 Jan 2021
REC opinion
Further Information Favourable Opinion