Exericse intervention in dementia patients_version0.1
Research type
Research Study
Full title
The effect of home-based exercise intervention in dementia patients on risk markers for dementia
IRAS ID
171111
Contact name
Sarah Aldred
Contact email
Sponsor organisation
University of Birmingham
Duration of Study in the UK
0 years, 5 months, 30 days
Research summary
Physical activity is beneficial for heath. There is wealth of evidence suggesting that exercise can prevent, and treat, cardiovascular disease, diabetes, hypertension, and dementia. However, little is known about the best form of exercise to benefit people suffering from dementia. There are currently several large randomised control trials being undertaken to assess the effect of physical activity in dementia patients (for example: ADEX, WHELD, ADMIT), and thus clearly there is an interest and need to assess the efficacy of physical activity in dementia. However, the focus of these studies is confined only to assessing cognitive function and quality of life; they do not provide any information on the pathological development of disease. Additionally, these measures are quantified using proxy rated questionnaires or via direct observational methods with both approaches having significant shortcomings.
This study will investigate the effect of a home-based exercise intervention, designed to increase physical activity levels of dementia patients, on markers of oxidative stress, cardiovascular health and quality of life. The study will examine the use/development of new movement sensor technology, to access the relationship of the patients’ activities with their behavior and bio markers of dementia.REC name
West Midlands - Coventry & Warwickshire Research Ethics Committee
REC reference
15/WM/0113
Date of REC Opinion
29 Apr 2015
REC opinion
Unfavourable Opinion