Exercise to manage fatigue in progressive MS
Research type
Research Study
Full title
Feasibility evaluation of a tailored exercise intervention to manage fatigue in progressive Multiple Sclerosis
IRAS ID
263733
Contact name
Scott Rooney
Contact email
Sponsor organisation
Glasgow Caledonian University
Duration of Study in the UK
0 years, 10 months, 0 days
Research summary
Fatigue is one of the most common and debilitating symptoms of Multiple Sclerosis (MS). Exercise is suggested as a way to improve fatigue, but it is not clear what the effects of exercise are on fatigue - especially in people with progressive MS. Therefore, this study aims to test the feasibility of a tailored exercise programme to help improve fatigue in people with progressive MS. To do this people with progressive MS who are experiencing fatigue will be randomly allocated to receive either a tailored exercise programme, a standard exercise programme, or their usual care. Both exercise programmes will be 8 weeks long and require participants to attend Falkirk Community Hospital twice a week. The standard exercise programme involves cycling on a stationary exercise bike for 30 minutes at a moderate intensity. The tailored exercise programme is similar to the standard exercise programme, as participants will perform the same type and amount of exercise; however, the difference between the 2 programmes is that the intensity of exercise performed during each session of the tailored exercise programme is dictated by the participant’s level of fatigue.
Participants will complete an exercise test, walking test, and questionnaires relating to fatigue, quality of life, depression and anxiety, sleep quality, and cognition before and 1 week after completing the exercise programme.
REC name
West of Scotland REC 5
REC reference
19/WS/0140
Date of REC Opinion
24 Sep 2019
REC opinion
Favourable Opinion