Exercise and Type 1 Diabetes Mellitus
Research type
Research Study
Full title
Nutritional strategies to effectively manage post-exercise glycaemic control in patients with Type 1 diabetes.
IRAS ID
217607
Contact name
S.D.R. Galloway
Contact email
Sponsor organisation
University of Stirling
Duration of Study in the UK
0 years, 8 months, 3 days
Research summary
This study aims to investigate the impact of two nutrition-based interventions on short term and longer term post-exercise glycaemic control in patients with type 1 diabetes. The first intervention will be focused on whether maintaining hydration status during exercise improves post-exercise glycaemic control. The second intervention examines whether provision of a carbohydrate supplement bolus immediately post-exercise can improve glycaemic control. Each of the interventions will be implemented separately. There is minimal evidence regarding the influence of hydration and carbohydrate supplementation on glycaemic control around exercise in patients with type 1 diabetes. Therefore, this study aims to fill a gap in the knowledge and aid in the formation of new specific exercise nutrition guidelines to promote effective glucose management around exercise in patients with type 1 diabetes. Participants will be eligible to complete the study if they have been diagnosed with Type 1 Diabetes for more than 5 years and regularly participate in endurance type exercise. Each participant will report to the laboratory over the course of 5 weeks for 3 experimental trials, each separated by 1 week. One experimental trial will involve participants maintaining euhydration during a 60 minute exercise period and then being provided with a carbohydrate supplement immediately post-exercise. One experimental trial will involve progressive dehydration of participants prior to, during and following the 60 min exercise, with no post-exercise carbohydrate supplement. The control trial will involve participants maintaining hydration throughout exercise with no carbohydrate supplement post-exercise. During exercise on all trials a solid carbohydrate source will be provided with an ingestion rate of 40g per hour to maintain normal glycaemia. Transdermal glucose monitors and an insulin dose diary will be used to track short and longer term glycaemic control. All visits will take place within the Faculty of Health Sciences and Sport at University of Stirling.
REC name
West of Scotland REC 4
REC reference
17/WS/0003
Date of REC Opinion
16 Feb 2017
REC opinion
Further Information Favourable Opinion