Evaluation Process For A Novel Disposable Cell Collection Device

  • Research type

    Research Study

  • Full title

    Evaluation process for the effectiveness, reliability and reproducibility of a Disposable cell collection Device (DCCD)

  • IRAS ID

    178450

  • Contact name

    Mr Kuchibhotla Satchi Swami

  • Contact email

    s.swami@nhs.net

  • Sponsor organisation

    Cytosystems Ltd

  • Duration of Study in the UK

    2 years, 0 months, 0 days

  • Research summary

    This study has been designed as part of the evaluation process for the effectiveness, reliability and reproducibility of a novel disposable device for the isolation and collection of urinary epithelial cells released from the bladder. This device will form part of a diagnostic test for determining the presence or otherwise of urothelial carcinoma in man. To date, the detection of this cancer using standard cytological preparations has proved costly and time consuming for both laboratory, scientific and medical staff.

    The rationale therefore is to develop a disposable device which can separate out bladder epithelial cells using specifically selected membranes in a closed pump arrangement. Such a device would isolate and preserve the cells immediately after void and these would then be sent to a pathology laboratory for analysis. The quality of cellular preservation is critical to the test to allow integrated analysis of cell morphology with the biomarker.

  • REC name

    North of Scotland Research Ethics Committee 1

  • REC reference

    15/NS/0038

  • Date of REC Opinion

    16 Jun 2015

  • REC opinion

    Further Information Favourable Opinion