EValuatiOn of MicrobiotaL ChANges In Head and Neck Cancer v 1.0
Research type
Research Study
Full title
EValuation of OraL, circulating and faecal Microbiotal ChANges in Patients with oral epithelial dysplasIa and Head and Neck Cancer. VOLCANIC
IRAS ID
293699
Contact name
James A McCaul
Contact email
Sponsor organisation
NHSGGC
Clinicaltrials.gov Identifier
researchregistry6735, Research Registry Registration
Duration of Study in the UK
3 years, 0 months, 4 days
Research summary
We will investigate the oral, circulating and faecal microbiome in patients with oral precancer changes in mucosa and in patients being treated for head and neck cancer. While traditional risk factors for head and neck cancer remain tobacco use and alcohol consumption, an increasing number of patients present without these risk factors present. The role of the microbiome is increasingly understood to be significant in carcinogenesis. We will compare the data generated with the known normal microbiota for the same geographical population to find differences which could be exploited to reduce cancer risk for this patient group.
REC name
East Midlands - Derby Research Ethics Committee
REC reference
21/EM/0105
Date of REC Opinion
14 Jun 2021
REC opinion
Further Information Favourable Opinion