Evaluating PREP

  • Research type

    Research Study

  • Full title

    Evaluating the clinical impact of the Prehabilitation and Recovery for Enabling Potential (PREP) clinical care pathway

  • IRAS ID

    369471

  • Contact name

    Marit Naomi Dugard

  • Contact email

    naomi.dugard@nhs.net

  • Sponsor organisation

    The Robert Jones and Agnes Hunt Orthopaedic Hospital

  • Duration of Study in the UK

    2 years, 0 months, 0 days

  • Research summary

    There is compelling clinical, methodological, and service-level rationale to implement and evaluate a veteran-specific prehabilitation and rehabilitation pathway. This proposed service, The Prehabilitation and Recovery for Enabling Potential (PREP) Programme, incorporates standardized outcome measures aligned with core domains for Total Knee Replacement (TKR), and addresses the biopsychosocial complexity unique to veteran populations. The PREP Programme aims not only to improve patient-level outcomes but also to contribute meaningful data to an underrepresented area of Orthopaedic rehabilitation research.
    The Evaluating PREP Research Study aims to determine in real-time whether the PREP Programme has an impact on clinical outcomes for Veterans undergoing TKR, and whether these are sustained for up to 12 months post-surgery.
    The research study plans to collect data from people undergoing the PREP Programme by extracting clinical data as they move through the clinical prehabilitation and rehabilitation programme. The study will also collect data from an additional questionnaire.

    Understanding whether individualised prehabilitation prior to TKR and intensive rehabilitation following surgery influences both physical and mental outcomes for Veteran patients could help improve surgical management in the future, leading to better outcomes for this patient population.

  • REC name

    London - Central Research Ethics Committee

  • REC reference

    26/LO/0251

  • Date of REC Opinion

    1 Apr 2026

  • REC opinion

    Favourable Opinion