Ester vs Salt Study (ESS)
Research type
Research Study
Full title
Comparing a ketone ester drink to a ketone salt drink for dietary ketosis
IRAS ID
184074
Contact name
Pete Cox
Contact email
Sponsor organisation
TdeltaS Ltd
Duration of Study in the UK
5 years, 0 months, 1 days
Research summary
Ketones are naturally produced by the body during starvation and can be used to power the body instead of sugar or fats. Evidence is accumulating that moderately raised ketone levels may have benefits in a variety of settings both in and out of a hospital. This study is designed to look at the differences between using a ketone salt drink and a ketone ester drink to artificially raise the levels of ketone bodies in the blood.
This study will involve four tests where drinks containing different amounts of ketone ester and ketone salt are consumed and the levels of ketones in the blood will be measured. It will be carried out at the University of Oxford. The amount of ketone in the blood will be measured by taking small blood samples at regular intervals. Urine will be collected to measure how much of the ketone is lost in this way. Participants will also be asked to regularly rate their feeling of fullness and if they are experiencing any side effects from the drink.
The data collected from each individual will be combined to illustrate the patterns. An understanding of these trends will be used to guide future studies using ketone drinks.
Subjects will be invited to participate via advertisement placed by study team members in the following locations: Oxford Daily Info, College Noticeboards, Hospital notice boards, Departmental notice boards, Sports Club/Centre notice boards.
REC name
South West - Frenchay Research Ethics Committee
REC reference
15/SW/0244
Date of REC Opinion
24 Aug 2015
REC opinion
Further Information Favourable Opinion