Establishment of an iPSC Bank to Investigate New Medicines (V1)

• Research type

  Research Tissue Bank

• IRAS ID

  229906

• Research summary

  REPROCELL Europe Induced Pluripotent Stem Cell Bank

• REC name

  West of Scotland REC 4

• REC reference

  17/WS/0163

• Date of REC Opinion

  11 Sep 2017

• REC opinion

  Unfavourable Opinion

• Data collection arrangements

  Tissue, blood and derived iPSC lines will be stored in the REPROCELL Europe Ltd iPSC Bank, based within REPROCELL Europe premises located in The West of Scotland Science Park, Glasgow. Relevant clinical data relating to each donor will also be collected and securely stored within the iPSC bank. Only REPROCELL staff will have access to collected data. All donated samples and data will be coded with a unique identifier that can only be decoded by the donors NHS healthcare team.
  Potential donors will be identified and approached while attending scheduled NHS appointments or inpatient admissions by a member of their clinical healthcare team. In some cases, potential donors may also be approached via a letter or telephone call from their clinical healthcare team. The donor will be given a Patient Information Booklet and consent form describing the nature of the bank, what is involved in terms of donation, and the potential research uses of the collected sample. If the donor consents, a sample will be taken and transferred to REPROCELL and the iPSC bank for processing and storage.

• Research programme

  The REPROCELL iPSC Bank will support a large research community both within the academic and pharmaceutical sectors. The primary research aim is to establish a bank of iPSC lines to investigate the biological mechanisms, efficacy and safety of new drugs and treatments. As such, the main research programmes will include (but are not limited to) disease modelling and mechanism studies, gene editing, drug development and discovery, early stage cellular therapy studies, toxicology screening and iPSC technology development.

• RTBTitle

  REPROCELL Europe Induced Pluripotent Stem Cell Bank

• Establishment organisation

  REPROCELL Europe Ltd

• Establishment organisation address

  Thonson Pavilion- Todd Campus

  West of Scotland Science Park

  Acre Road, Glasgow

  G20 0XA