ERP/HR TOCD RTC
Research type
Research Study
Full title
INTEGRATING EXPOSURE AND RESPONSE PREVENTION AND HABIT REVERSAL TECHNIQUES TO TREAT A TOURETTIC SUBTYPE OF OBSESSIVE-COMPULSIVE DISORDER (TOURETTIC OCD).
IRAS ID
349759
Contact name
Himanshu Tyagi
Contact email
Sponsor organisation
University College London
Clinicaltrials.gov Identifier
Z6364106/2024/08/162 Health Research, University College London
Duration of Study in the UK
4 years, 10 months, 29 days
Research summary
The symptom overlap between Tic Disorders (TD) and Obsessive Compulsive Disorder (OCD) has continued to spark interest over the decades. Independently, these neuropsychiatric disorders have been the subject of intense speculation since at least the eighteenth century. Despite the overt symptomology associated with both, a subcategory of patient(s) (i.e., those with a Tourettic Subtype of Obsessive-Compulsive Disorder) exist that seek treatment with distinct set of symptoms that are similar to both TD and OCD yet remarkably different. Standardized treatments are most commonly provided to this patient population, yet these interventions seldom address the overlapping features of their clinical presentation.
TRIAL PARTICIPANTS TO BE RANDOMIZED INTO ONE OF THE FOUR TRIAL ARMS (I.E., GROUP 1: HYBRID COMBINATION OF EXPOSURE AND RESPONSE PREVENTION AND HABIT REVERSAL TRAINING, GROUP 2: PURE EXPOSURE AND RESPONSE PREVENTION; GROUP 3: PURE HABIT REVERSAL TRAINING; AND GROUP 4: ACTIVE SUPPORTIVE PSYCHOTHERAPY AND PSYCHOEDUCATION CONTROL). ALL TRIAL ARMS WILL BE COMPRISED OF TWELVE CONSECUTIVE WEEKS OF ONE-TO-ONE FACE-TO-FACE SIXTY MINUTE PSYCHOTHERAPY APPOINTMENTS AND A FOLLOW-UP APPOINTMENT AT WEEK TWENTY-FOUR
By introducing a contemporary framework of investigation, casting a light on this clinical phenomenon (i.e., Tourettic Subtype of Obsessive-Compulsive Disorder) may well fill in gaps in the literature. Perhaps, most importantly, it is believed that this progressive step will assist (i) clinicians in determining the optimal strategy or sequence of strategies for addressing the symptom blend by providing empirically informed recommendations on diagnostics, treatment, and prognosis and (ii) patients in terms of accessing suitable and appropriate healthcare.
REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
25/NE/0058
Date of REC Opinion
29 May 2025
REC opinion
Further Information Favourable Opinion