Episodic medication adherence in PHIV+ adolescents

  • Research type

    Research Study

  • Full title

    A within-subjects investigation of episodic antiretroviral medication adherence in adolescents with perinatally infected HIV

  • IRAS ID

    154311

  • Contact name

    Amy L Hawkins

  • Contact email

    amy.hawkins.2012@live.rhul.ac.uk

  • Sponsor organisation

    Royal Holloway University of London

  • Research summary

    Antiretroviral therapy requires optimal adherence to be successful in managing HIV. Factors which influence non-adherence are critical to understanding medication management, particularly with perinatally infected HIV+ youth who are likely to have complex treatment histories and are experiencing the developmental challenges of adolescence. This study aims to investigate within-subjects situational differences in adherent and non-adherent episodes, informed by theory (the Information-Motivation-Behavioral Skills [IMB] model) and using both retrospective and prospective data collection. Self-efficacy, outcome expectancy and other motivation factors will be investigated. Contextual variables including situational mood, substance use and stable or changes in usual routine will also be explored.

  • REC name

    South Central - Berkshire B Research Ethics Committee

  • REC reference

    14/SC/1019

  • Date of REC Opinion

    27 Jun 2014

  • REC opinion

    Further Information Favourable Opinion