Epidemiology of Tumours of the Central Nervous System
Research type
Research Study
Full title
Tumours of the Central Nervous System: Incidence, Survival and Variation in Treatments
IRAS ID
258271
Contact name
Usama Ali
Contact email
Sponsor organisation
University of Oxford
Duration of Study in the UK
2 years, 8 months, 30 days
Research summary
Over the past 50 years, central nervous system (CNS) tumours have become more and more common and the long term effects of a diagnosis in terms of a patient’s day to day health have become a major concern. To better understand this condition, it is important to see how trends have changed over a long period of time, and whether these trends can explain patient outcomes. There are a number of treatments available for patients and there is growing evidence that not all patients in the UK may have access to the same level and standard of care.
This study aims to describe trends in the incidence of all primary CNS tumours since 1971 and to assess whether these trends vary according to where patients reside in the UK or if they vary based on patient characteristics such as age, gender, ethnicity, social class etc. We will also aim to explore trends in the types of surgery/treatment being offered to patients since 1971, to identify variation in treatments. This will allow us to see if inequalities exist and whether they are widening over time.
Gaining a better understanding of the management of patients and their treatment pathways will, in the long term, benefit the public health system by helping to prevent or reduce unwarranted morbidity and mortality, in addition to providing patients with a better opportunity of treating and managing their diagnosis.
REC name
London - London Bridge Research Ethics Committee
REC reference
19/LO/0247
Date of REC Opinion
6 Feb 2019
REC opinion
Favourable Opinion