Epidemiology of Hodgkin and Non-Hodgkin lymphoma
Research type
Research Study
Full title
Hodgkin and Non-Hodgkin Lymphoma: Using routine data to identify recurrence, variation in the use of radiotherapy, and late-effects of treatment.
IRAS ID
263352
Contact name
Rebecca Shakir
Contact email
Sponsor organisation
University of Oxford, Clinical Trials and Research Governance
Duration of Study in the UK
2 years, 9 months, 6 days
Research summary
Lymphoma is a form of cancer which is very sensitive to treatment, both with chemotherapy and radiotherapy. Significant variation in the use of radiotherapy was identified in a report in 2015, which may be more related to geographical and organisational factors rather than patient or disease factors. This project aims to undertake further analysis to understand the causes and clinical impact of this variation on patient outcomes.
Running alongside this, we aim to use the routine datasets available within Public Health England (PHE) to further understand subsequent relapse and recurrence of lymphoma. Factors predicting recurrence will be identified and use to develop a model to help predict those patients who may experience recurrence of their lymphoma following standard treatment.
The final aspect of analysis will be to look at what long-term side-effects survivors of lymphoma develop. In particular, we will analyse the incidence of heart disease, stroke and subsequent cancers.REC name
South Central - Oxford B Research Ethics Committee
REC reference
19/SC/0227
Date of REC Opinion
18 Apr 2019
REC opinion
Favourable Opinion